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Coronavirus-disease-2019-induced antiphospholipid-like syndrome: a case report

Fatemeh Bahramnezhad1,2, Banafsheh Ghorbani3, Meysam Ghaedrahamt4

  • 1Nursing and Midwifery Care Research Center, School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran.

Journal of Medical Case Reports
|July 29, 2021
PubMed

Insights

Coronavirus disease 2019 can cause an antiphospholipid syndrome-like condition. Elevated antiphospholipid antibodies in COVID-19 patients may lead to misdiagnosis, highlighting the importance of differential diagnosis for proper treatment.

Area of Science:

  • Internal Medicine
  • Infectious Diseases
  • Rheumatology

Background:

  • Coronavirus disease 2019 (COVID-19) presents diagnostic and therapeutic challenges.
  • Thrombosis and coagulation abnormalities are significant causes of mortality in COVID-19 patients.
  • Differential diagnosis is crucial for managing thrombotic events in COVID-19.

Observation:

  • A 56-year-old male patient developed thrombosis and elevated antiphospholipid antibodies post-cardiac surgery.
  • Initial presentation suggested antiphospholipid syndrome (APS).
  • COVID-19 diagnosis was confirmed via PCR and CT scan.

Findings:

  • Elevated antiphospholipid antibodies in COVID-19 patients can mimic APS.
  • Misdiagnosis can occur in the absence of reliable COVID-19 testing.
  • This case highlights a COVID-19-induced APS-like condition.

Implications:

  • Accurate and timely diagnosis of COVID-19 is essential.
  • Awareness of potential APS-like conditions in COVID-19 is critical for appropriate patient management.
  • Differential diagnosis strategies are vital for preventing delayed or incorrect treatment.
Abstract

Keywords:
AntibodiesAntiphospholipidAntiphospholipid syndromeCOVID-19

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