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Plurihormonal pituitary macroadenoma: a case report
Ebtesam Allehaibi1, Mussa H AlMalki2,3, Imad Brema2
1Obesity, Endocrine, and Metabolism Center, King Fahad Medical City, Riyadh, Saudi Arabia. esallehaibi@gmail.com.
Journal of Medical Case Reports
|July 29, 2021
Summary
This case report details a rare plurihormonal pituitary adenoma secreting multiple hormones, presenting with mass effect symptoms rather than typical hormonal dysfunction. It emphasizes the need for comprehensive immunohistochemical analysis for accurate diagnosis and management of these unusual pituitary tumors.
Area of Science:
- Endocrinology
- Oncology
- Neurosurgery
Background:
- Plurihormonal pituitary adenomas secrete multiple hormones, accounting for 10-15% of pituitary tumors, but rarely cause clinical hypersecretion.
- Commonly co-secrete growth hormone and prolactin, with acromegaly being the most frequent clinical manifestation.
- Often considered clinically silent, making their presentation challenging and requiring thorough investigation.
