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In vitro metabolic study of EGYT-3615 using rat liver microsomes
1Department of Pharmacodynamics, Semmelweis University of Medicine, EGIS Pharmaceutical Works, Budapest, Hungary.
Polish Journal of Pharmacology and Pharmacy
|March 1, 1987
Abstract:
In vitro metabolism of EGYT-3615, a prospective new antidepressant was studied by using rat liver microsomes. The metabolite (M) found in earlier in vivo studies was unanimously found to be the product of a microsomal enzymatic process. The Michaelis-Menten constant of the reaction was calculated.