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Related Experiment Video

Updated: Oct 26, 2025

Intraoperative Gastroscopy for Tumor Localization in Laparoscopic Surgery for Gastric Adenocarcinoma
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Gastric Cancer Screening Methods: A Comparative Study of Two Scoring Methods.

Weixing Zhang1, Zhangzhi Li2, Muhammad Safwan Akram3

  • 1Department of Critical Care Medicine, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, People's Republic of China.

Cancer Management and Research
|July 29, 2021
PubMed
Summary

Li

Keywords:
Japanese scoringLi’s scoringearly gastric cancer

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Area of Science:

  • Gastroenterology
  • Oncology
  • Medical Diagnostics

Background:

  • Early gastric cancer (EGC) screening is crucial for improving patient outcomes.
  • Existing screening methods require evaluation for efficacy in diverse populations.

Purpose of the Study:

  • To compare the effectiveness of Li's scoring and the Japanese scoring method for EGC screening in a healthy Chinese population.
  • To determine which scoring method offers superior sensitivity and specificity.

Main Methods:

  • A cohort of 342 healthy volunteers (aged 40-74) underwent screening using both Li's and Japanese scoring methods.
  • Receiver Operating Characteristic (ROC) curves were generated based on endoscopic and pathological results.
  • Sensitivity and specificity were calculated to assess diagnostic accuracy.

Main Results:

  • Li's scoring demonstrated a higher area under the ROC curve (0.837) compared to the Japanese score (0.763).
  • Li's scoring achieved superior sensitivity (63.60%) and specificity (91.10%) versus the Japanese score (54.50% sensitivity, 87.50% specificity).
  • The differences in performance between the two scoring methods were statistically significant (P<0.05).

Conclusions:

  • Both Li's and Japanese scoring methods show promise for EGC screening in healthy individuals.
  • Li's scoring method exhibits greater sensitivity and specificity, suggesting it is a more effective tool for EGC screening in this population.