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Updated: Oct 26, 2025

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
Published on: February 8, 2022
Diagnostic Fleischner's sign in atrial septal defect
1Department of Cardiovascular Center The Seventh Affiliated Hospital Sun Yat-sen University Shenzhen China.
The Fleischner sign is uncommon in adults with atrial septal defect (ASD) unless it is undiagnosed. In adults presenting with the Fleischner sign, congenital heart disease should be considered.
Area of Science:
- Cardiology
- Medical Diagnostics
Background:
- The Fleischner sign is a rare finding in patients with atrial septal defect (ASD).
- Its presence in adulthood often suggests an undiagnosed condition.
Purpose of the Study:
- To highlight the association between the Fleischner sign and undiagnosed ASD in adults.
- To emphasize the importance of considering congenital heart disease in adults with the Fleischner sign.
Main Methods:
- Case review and literature analysis were performed.
- Diagnostic criteria for ASD and Fleischner sign were examined.
Main Results:
- The Fleischner sign is infrequently observed in adult patients with ASD.
- Undiagnosed ASD can lead to the Fleischner sign in adulthood.
Conclusions:
- The Fleischner sign in adults warrants consideration of congenital heart disease, particularly undiagnosed ASD.
- Early diagnosis and management of ASD are crucial to prevent such rare presentations.
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