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Updated: Oct 26, 2025
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Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
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Pregnancy denial: a complex symptom with life context as a trigger? A prospective case-control study.
Summary
Pregnancy denial is linked to unstable relationships, lower education, and psychiatric history. Advanced maternal age offers protection, while past denial and contraceptive use are significant risk factors.
Area of Science:
- Reproductive Health
- Psychiatry
- Sociology
Background:
- Pregnancy denial, a complex phenomenon, presents significant challenges in maternal and child healthcare.
- Understanding the multifactorial etiology of pregnancy denial is crucial for timely intervention and support.
Purpose of the Study:
- To identify key risk factors associated with pregnancy denial in women.
- To elucidate the demographic, social, medical, and psychiatric predictors of pregnancy denial.
Main Methods:
- A prospective case-control study involving 71 mother-infant dyads with pregnancy denial and 71 controls.
- Data collection post-delivery included observational leaflets and psychiatric assessments (MINI, QSSP).
Main Results:
- Significant risk factors for pregnancy denial included unstable relationships (OR 17.18), lack of a high school diploma (OR 1.11), and psychiatric history (OR 6.33).
- Advanced maternal age was protective (OR 0.86). Past pregnancy denial (personal or family history) and contraceptive use (especially oral contraceptives) were also risk factors.
Conclusions:
- A history of pregnancy denial, whether personal or familial, warrants systematic inquiry during prenatal care.
- Life context factors such as young age, single status, socioeconomic instability, and contraceptive use can precipitate pregnancy denial.
Keywords:
Ageeducationlife contextmarital statusnewbornpregnancy denialpsychiatric backgroundrisk factorsMore Related Videos
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