A highly sensitive chemosensor for rapid recognition of Cu²⁺ and HSO₃^- in 100% aqueous solution

Dual-responsive chemosensors have garnered much research interests owing to the ability of recognizing two analytes simultaneously. Herein, the chemosensor BPIS composed of hemicyanine and 2, 2'-dipyridylamine (DPA) was facilely synthesized for sensitive and expeditious recognition of Cu²⁺ and HSO₃^- in 100% aqueous solution. By adding Cu²⁺, BPIS showed substantial spectral changes accompanied by a noticeable color change from pink to yellow under daylight. The absorbance and fluorescence intensity were linearly correlated to the Cu²⁺ concentration, enabling the quantitative recognition of Cu²⁺. The limit of detection (LOD) for Cu²⁺ was down to 4.02 × 10^-9 M. The response time of BPIS towards Cu²⁺ was 10 s, imparting BPIS great potential in real-time detection of Cu²⁺. Meanwhile, BPIS manifested ratiometric fluorescence response by introducing HSO₃^- owing to the 1,4-addition between HSO₃^- and the unsaturated CC bond of BPIS. The color of the BPIS solution progressively faded from pink to colorless with increasing HSO₃^- concentration, and a LOD of 3.47 × 10^-9 M was obtained. In addition, BPIS-coated test paper was found to be an efficient tool for fast, sensitive, portable detection of Cu²⁺ and HSO₃^- by naked eyes. More importantly, the precise detection of Cu²⁺ and HSO₃^- in real water and sugars were realized, respectively, by capitalizing on BPIS as the signal tool.