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Time to a Negative SARS-CoV-2 PCR Predicts Delayed Return to Work After Medical Leave in COVID-19 Infected Health
Jaime Villarreal1, Sandra Valeria Nieto, Fabián Vázquez
1Department of Occupational Health and Prevention, Fundacioń Jimeńez Diaz University Hospital, Madrid, Spain (Dr Villarreal, Dr Nieto, Dr Vázquez, and Dr del Campo); Epidemiology and Statistics Unit, Health Research Institute, Fundacioń Jimeńez Diaz University Hospital, Madrid, Spain (Dr Mahillo); Division of Occupational Medicine, Icahn School of Medicine at Mount Sinai, New York, New York (Dr de la Hoz).
Objective:
To investigate whether HCWs return to work (RTW) after COVID-19 was associated with time to a negative viral detection test.
Methods:
To evaluate the association of RTW with an undetectable RT-PCR adjusting for different factors.
Results:
Three hundred seventy-five HCWs who required medical leave for COVID-19 at a hospital in Madrid. Multivariable analyses confirmed the association of delayed RTW with interval to negative PCR (ORadj 1.12, 95% CI 1.08, 1.17) as well as age, sex, and nursing staff and clinical support services compared to physicians. A predictive model based on those variables is proposed, which had an area under the receiver operating curve of 0.82.
Conclusions:
Delayed RTW was associated with longer interval to a negative RT-PCR after symptom onset, adjusting for occupational category, age, and sex.
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