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Related Experiment Video

Updated: Oct 26, 2025

A Novel Surgical Technique As a Foundation for In Vivo Partial Liver Engineering in Rat

A Novel Surgical Technique As a Foundation for In Vivo Partial Liver Engineering in Rat

Published on: October 6, 2018

The development of artificial livers.

Asish C Misra¹, Devin Eckhoff

¹Department of Surgery, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.

Current Opinion in Organ Transplantation

|July 29, 2021

Summary

This summary is machine-generated.

Artificial liver technologies are being developed to address the shortage of donor livers for patients with liver failure. Novel approaches show promise for improving patient outcomes.

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Last Updated: Oct 26, 2025

A Novel Surgical Technique As a Foundation for In Vivo Partial Liver Engineering in Rat

A Novel Surgical Technique As a Foundation for In Vivo Partial Liver Engineering in Rat

Published on: October 6, 2018

Decellularization and Recellularization of Whole Livers

Decellularization and Recellularization of Whole Livers

Published on: February 4, 2011

Author Spotlight: Utilization of Decellularized Spleen Matrix for Bioartificial Livers

Author Spotlight: Utilization of Decellularized Spleen Matrix for Bioartificial Livers

Published on: February 9, 2024

Area of Science:

Biomedical Engineering
Regenerative Medicine
Hepatology

Background:

Liver transplantation is a standard treatment for liver failure.
Donor liver scarcity limits transplantation accessibility.
Bridging technologies are essential for managing liver failure.

Purpose of the Study:

To review the development of artificial liver technologies.
To discuss current advancements and future directions in artificial liver research.

Main Methods:

Review of existing literature on artificial liver devices.
Analysis of clinical data for current liver assist technologies.
Exploration of emerging materials and tissue engineering techniques.

Main Results:

Current liver assist devices have limited demonstrated survival benefits.
Ongoing clinical trials are evaluating the efficacy of existing devices.
Advances in materials science and tissue engineering are driving innovation.

Conclusions:

Novel artificial liver technologies are under development.
Sophisticated 3D materials are being utilized in new designs.
These emerging technologies aim to improve outcomes for liver failure patients.