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COVID-19, Acute Lymphoblastic Leukemia, and Down Syndrome: A Short Review and a Case Report
Ahmed Arafat1,2, Dinara Sadykova1,2, Ayrat Ziatdinov1,2
1Kazan State Medical University, Kazan, Russian Federation.
Insights
This study details a pediatric case of relapsed precursor B-cell acute lymphoblastic leukemia in a child with Down syndrome who contracted COVID-19. It outlines the treatment regimen used for this complex oncology patient during the pandemic.
Area of Science:
- Pediatric Oncology
- Infectious Diseases
- Genetics
Background:
- COVID-19 presents treatment challenges, with limited data on immunocompromised pediatric oncology patients.
- Children with Down syndrome and cancer are a vulnerable population during the SARS-CoV-2 pandemic.
Abstract:
SARS-CoV-2 which causes COVID-19 has been a great challenge to treat and deal with; despite strict measures that had been implemented by governments and organizations, worrying rates of morbidity and mortality are still being reported. Although available data have expressed that moderate or even mild forms of the disease are expected amongst most pediatrics cases, minimal data are available on the prognosis and the disease's complications on the immunocompromised, especially oncology patients. We report a case of relapsed precursor B-cell acute lymphoblastic leukemia of a child with Down syndrome and COVID-19 and outline the treatment regimen that we used.
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