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Development and Human Factors Considerations for Extended Reality Applications in Medicine: The Enhanced
Jennifer N Avari Silva1,2,3, Mary Beth Privitera4, Michael K Southworth3
1Department of Pediatrics, Cardiology. Washington University in St Louis, School of Medicine, St Louis, MO.
Summary
This study outlines considerations for developing medical applications in extended realities (XRs), using the Enhanced ELectrophysiology Visualization and Interaction System (ĒLVIS) as a case study for human factors testing.
Area of Science:
- Medical technology
- Human-computer interaction
- Extended Reality (XR) development
Background:
- The proliferation of extended reality (XR) hardware has spurred diverse applications across engineering, entertainment, and medicine.
- Medical XR applications require specialized development and human factors testing considerations.
- Understanding user constraints and use cases is crucial for iterative improvement in XR medical tools.
Purpose of the Study:
- To discuss key considerations for developing and conducting human factors testing for XR applications in medicine.
- To present the Enhanced ELectrophysiology Visualization and Interaction System (ĒLVIS) as an illustrative example.
- To report usability and interpersonal interaction data from the initial human testing of ĒLVIS.
Main Methods:
- The manuscript details the development process and human factors testing protocols for XR medical applications.
- The Enhanced ELectrophysiology Visualization and Interaction System (ĒLVIS) was utilized as a practical case study.
- First-in-human testing was conducted to gather usability and interaction data.
Main Results:
- The study highlights specific challenges and best practices in XR medical application development.
- Usability data from the ĒLVIS system was collected and analyzed.
- Critical interpersonal interaction data was obtained during the initial human trials of ĒLVIS.
Conclusions:
- Iterative development informed by user constraints and use-case specific testing is vital for effective medical XR applications.
- The ĒLVIS system demonstrates the practical application of these development and testing considerations.
- Findings from the first-in-human testing provide valuable insights for future medical XR development and deployment.

