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Published on: February 10, 2023
Radiologic Imaging Modalities for Colorectal Cancer
Wen Liu1, An-Rong Zeng2, Han-Zhou Tang2
1Department of Radiology, Jinshan Hospital, Fudan University, 1508 Longhang Rd., Jinshan District, Shanghai, 201508, China. liuwenwenliu5th@163.com.
Computed tomography colonography (CTC) and magnetic resonance colonography (MRC) show high diagnostic value for colorectal cancer (CRC) detection. Positron emission tomography/computed tomography (PET/CT) is valuable for identifying local recurrence in CRC patients.
Area of Science:
- Radiology
- Oncology
- Medical Imaging
Background:
- Colorectal cancer (CRC) diagnosis and management rely on various radiologic imaging modalities.
- The diagnostic performance of different imaging techniques for CRC varies.
Purpose of the Study:
- To summarize the diagnostic and management capabilities of computed tomography colonography (CTC), magnetic resonance colonography (MRC), and positron emission tomography (PET)/computed tomography (CT) for colorectal cancer (CRC).
Main Methods:
- A comprehensive literature search was conducted across PubMed, EmBase, and the Cochrane library for studies published before April 2021.
- Diagnostic performance data for CTC, MRC, and PET/CT in CRC detection were extracted and analyzed.
Main Results:
- Fifty-four studies were analyzed: 17 for CTC, 8 for MRC, and 29 for PET/CT.
- Pooled sensitivity and specificity were high for all modalities: CTC (0.97, 0.99), MRC (0.98, 0.94), and PET/CT (0.94, 0.94).
- Area under the curve (AUC) values were 1.00 for CTC, 0.99 for MRC, and 0.97 for PET/CT.
Conclusions:
- Computed tomography colonography (CTC) and magnetic resonance colonography (MRC) demonstrate significant diagnostic value for colorectal cancer (CRC) detection.
- Positron emission tomography/computed tomography (PET/CT) shows higher diagnostic value in detecting local recurrence among patients with CRC.
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