Facile synthesis of Ag@C@Ag hybrid nanoparticles as SERS substrate

Ag@C core-shell nanoparticles (NPs) were first prepared by a low-temperature heating-stirring method and subsequently modified with polyethyleneimine (PEI) at different concentrations. Finally, Ag@C@Ag hybrid NPs were prepared by a simple self-assembly procedure, and 24-nm Ag NPs were attached onto the surface of the initially fabricated PEI-modified Ag@C NPs via interaction between the NH₂ groups of PEI and Ag. The results demonstrated that rhodamine 6G (R6G) could be detected at a concentration as low as 10^-10 M using the Ag@C@Ag NPs as a substrate. To further understand the signal enhancement mechanism, finite-difference time-domain (FDTD) simulations were performed to calculate the electromagnetic field distributions and illustrate the generated Raman hot spots. The FDTD indicated that this enhancement was attributed to the surface plasmon resonance effects of the core Ag NPs in the Ag@C NPs, hot spots between the Ag@C NPs, and external assembly of the 24-nm Ag NPs, as well as between the massive outlayer 24-nm Ag NPs themselves. These fabricated materials were further applied for the detection of folic acid as an actual sample. The outstanding performance of the Ag@C@Ag NPs can be attributed to both the excellent properties of this hybrid substrate and the absorption capability of the carbon layer. Thus, this Ag@C@Ag NP material demonstrates excellent and stable optical properties, and can be used as a surface-enhanced Raman scattering (SERS) substrate in the field of ultrasensitive spectral analysis. Graphical abstract Ag@C@Ag hybrid nanoparticles are prepared by a simple self-assembly method. Then the synthesized Ag@C@Ag hybrid nanoparticles are used as SERS substrate for folic acid detection. To further understand the signal enhancement mechanism, finite-difference time-domain simulations are performed to calculate the electromagnetic field distributions and illustrate the generated SERS hot spots.