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Related Concept Videos

The Thyroid Gland01:23

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The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
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Synthesis and Regulation of Thyroid Hormones01:20

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Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
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Functions of Thyroid Hormones01:18

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The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
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Myocarditis II: Clinical Features and Diagnostic Tests01:27

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Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
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Myocarditis I: Introduction01:21

Myocarditis I: Introduction

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Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
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Myocarditis III: Medical Management01:14

Myocarditis III: Medical Management

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Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...
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Updated: Oct 26, 2025

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
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Coronavirus Disease 2019-Induced Thyroiditis.

Nicolas Ramsay1, Rene Carizey1, Daniel Popa1

  • 1Department of Emergency Medicine, Rush University Medical Center, Chicago, Illinois.

The Journal of Emergency Medicine
|August 1, 2021
PubMed
Summary
This summary is machine-generated.

Coronavirus Disease 2019 (COVID-19) can cause thyroiditis, presenting with symptoms like chest pain and neck discomfort. Emergency physicians should consider this diagnosis, as it mimics other serious conditions.

Keywords:
COVID-19SARS-CoV-2coronavirus disease 2019viral thyroiditis

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Area of Science:

  • Endocrinology
  • Infectious Diseases

Background:

  • Coronavirus Disease 2019 (COVID-19) presents with acute respiratory symptoms and poorly understood sequelae.
  • Thyroid dysfunction is an emerging, yet under-recognized, complication of COVID-19.

Observation:

  • A 51-year-old woman with recent COVID-19 diagnosis presented with chest pain, palpitations, dysphagia, and neck discomfort.
  • Clinical presentation mimicked other emergent conditions such as pulmonary embolism.

Findings:

  • The patient was diagnosed with COVID-19-induced thyroiditis.
  • Treatment included propranolol and nonsteroidal anti-inflammatory medication.

Implications:

  • Emergency physicians must consider thyroiditis in patients with COVID-19 presenting with relevant symptoms.
  • Awareness of COVID-19-induced thyroiditis aids in appropriate evaluation and management, preventing misdiagnosis.
  • Caution is advised regarding iodinated contrast media in patients with potential thyroid dysfunction.