Related Experiment Video
Updated: Aug 19, 2026

A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level
Published on: January 19, 2024
Prevalence of thalassaemias in ethnic Saudi Arabians
K Ganeshaguru1, J K Acquaye, A P Samuel
1Haemoglobinopathy Unit, King Fahd Medical Research Center, Jeddah, Saudi Arabia.
Abstract:
A study of the prevalence of alpha- and beta-thalassaemia and the sickle cell gene was carried out on 840 healthy adult male Saudi Arabians of different tribal origins. Complete blood count, haemoglobin electrophoresis and HbA2 estimation were carried out on all. Globin biosynthetic analysis was carried out on all 85 subjects with microcytic red cells and on 180 randomly selected subjects with normal red cell indices. The results showed prevalence of beta-thalassaemia of 3.0%, alpha/beta thalassaemia of 0.9%, alpha-thalassaemia of 43.3% and sickle trait of 5.7%. There were tribal variations in the prevalence of both alpha-thalassaemia and the sickle gene.
Related Concept Videos
Pedigree Analysis
Translation
Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of Life
Alternative RNA Splicing
There are five types of alternative RNA splicing that vary in the ways the pre-mRNA segments are removed or retained in the mature mRNA. The first...
Translation
Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of Life
Disorders of Erythrocytes
Erythrocyte disorders can be broadly categorized into two main types: anemic and polycythemic conditions.
A low oxygen-carrying capacity of the blood due to the loss, lower production, or destruction of erythrocytes is termed anemia. Hemorrhagic anemia, for example, occurs when bleeding from an external wound or internal ulcer reduces erythrocyte counts.
On the other...
Pharmacogenetics of Drug Targets: β₂-Adrenergic Receptors, Apo E, Thymidylate Synthase
