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Updated: Oct 26, 2025

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia

Published on: December 19, 2020

COVID-19 and lung pathologies.

Darshana Purohit¹, Ashok Kumar Ahirwar², Apurva Sakarde²

¹All India Institute of Medical Sciences, Nagpur, Maharashtra, India.

Hormone Molecular Biology and Clinical Investigation

|August 1, 2021

Summary

COVID-19, caused by the SARS-CoV-2 virus, presents varied symptoms and risks. Pre-existing conditions like COPD and cancer increase susceptibility, while asthma is not a major risk factor.

Keywords:

COVID-19 SARS-CoV-2 cytokine storm lung pulmonary

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Area of Science:

Infectious Diseases
Pulmonology
Virology

Background:

COVID-19 is a global health emergency caused by the SARS-CoV-2 virus, a highly infectious RNA virus.
Disease manifestations range from asymptomatic to severe pneumonia and Acute Respiratory Distress Syndrome (ARDS).
Comorbidities significantly influence infection risk and disease severity.

Purpose of the Study:

To review the impact of various comorbidities on COVID-19 risk and severity.
To analyze the relationship between specific conditions and SARS-CoV-2 infection.
To highlight the current understanding of COVID-19's clinical presentation and risk factors.

Main Methods:

Literature review and analysis of existing COVID-19 research.
Examination of epidemiological data and clinical observations.
Focus on comorbidities such as asthma, COPD, tuberculosis, cancer, autoimmune disorders, and fungal infections.

Main Results:

Asthma and allergies are not identified as major COVID-19 risk factors.
COPD patients, particularly smokers, show higher ACE-2 expression and increased risk.
Cancer patients, especially lung cancer, and those with autoimmune disorders or fungal infections face higher infection risk and severity.

Conclusions:

Comorbidities play a crucial role in COVID-19 susceptibility and outcomes.
Understanding these associations is vital for risk stratification and patient management.
Further research is needed to explore specific treatment modalities and long-term effects.