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[Phospholipids bound with plasma proteins in children with vitamin D-deficient rickets]
Insights
Children with vitamin-D-deficient rickets show significant changes in plasma phospholipids. Phospholipids in lipoproteins increase, while those bound with fibrinogen decrease, indicating altered lipid metabolism in rickets.
Area of Science:
- Biochemistry
- Pediatrics
- Nutritional Science
Abstract:
Composition of phospholipids bound with plasma proteins in the healthy children and in those with vitamin-D-deficient rickets are studied. It is found that the quantitative and qualitative content of phospholipids in the low- and high-density lipoproteins increases considerably with the rickets. At the same time the content of phospholipids which form complexes wit fibrinogen gets two times lower. The character of changes in the phospholipid composition in protein fractions and in the whole plasma in case of rickets is different.