Related Experiment Video
Updated: Oct 26, 2025
07:28
Dry Powder and Nebulized Aerosol Inhalation of Pharmaceuticals Delivered to Mice Using a Nose-only Exposure System
Published on: April 6, 2017
40.9K
Pharmacist involvement in the inhaler choice improves lung function in patients with COPD: a prospective single-arm
Eiji Shiwaku1, Satoshi Dote2, Shinobu Kaneko1
1Department of Pharmacy, Kyoto-Katsura Hospital, 17, Yamadahiraocho, Kyoto-shi Nishikyo-ku, Kyoto, 615-8256, Japan.
Journal of Pharmaceutical Health Care and Sciences
|August 2, 2021
Summary
Pharmacist involvement in selecting inhalers for chronic obstructive pulmonary disease (COPD) patients improved lung function and adherence. This task shift enhances pharmacotherapy quality and reduces physician workload.
Area of Science:
- Pulmonology
- Clinical Pharmacy
Background:
- Task shifting from physicians to hospital pharmacists is emerging in Japan to optimize pharmacotherapy.
- This study evaluated the impact of pharmacist-led inhaler selection on chronic obstructive pulmonary disease (COPD) patient outcomes.
Purpose of the Study:
- To investigate the clinical outcomes of patients with newly diagnosed COPD when pharmacists are involved in inhaler selection.
- To assess the safety and efficacy of pharmacist-led inhaler choice protocol.
Main Methods:
- A prospective, single-arm study involving 36 newly diagnosed COPD outpatients.
- Pharmacists assessed patient's inhalation technique, comprehension, and physical ability to recommend a personalized inhaler using a developed protocol.
- Pulmonologists prescribed the pharmacist-selected inhaler, with primary endpoint being FEV1 improvement at 26 weeks.
Main Results:
- Mean FEV1 significantly increased from baseline to 26 weeks (p < 0.0001).
- Significant improvements were observed in COPD Assessment Test (CAT), mMRC, and ASK-20 scores.
- 86% of patients were CAT responders, and no exacerbations occurred during the study.
Conclusions:
- Pharmacist involvement in inhaler selection for COPD patients led to better lung function, health status, and adherence.
- The transfer of inhaler selection from physicians to hospital pharmacists is feasible and safe when guided by a protocol.
Related Concept Videos
01:23Inhaled Medications
490
Inhaled medications are crucial for managing chronic obstructive pulmonary disease (COPD) and asthma. They are essential for effective treatment and control, ensuring optimal respiratory health and well-being. Inhaled medication delivers drugs directly to the lungs, providing a rapid onset of action and reducing systemic side effects compared to oral or injectable medications. Three primary types of inhalation devices are used to administer these medications: nebulizers, metered-dose inhalers...
490
01:26COPD: Management Using Bronchodilators and Corticosteroids
494
Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
494
01:29Chronic Obstructive Pulmonary Disease-V: Management
2.8K
Managing Chronic Obstructive Pulmonary Disease (COPD) involves a multifaceted approach to reduce symptoms, prevent exacerbations, improve overall health status, and slow disease progression. Key strategies include lifestyle modifications, pharmacotherapy, supportive therapies, and, in some cases, surgery. Here is an overview of the primary COPD management strategies:
Smoking Cessation
Smoking Cessation
2.8K
01:30Asthma-IV: Diagnostic and Management
2.7K
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
2.7K
01:17Drugs Used in Lower Respiratory Disorders: Overview
730
Lower respiratory tract disorders present challenges that often require skilled and nuanced approaches for effective management. Common ailments, such as asthma and chronic obstructive pulmonary disease (COPD), have prompted the development of intricate treatment strategies involving bronchodilators and anti-inflammatory drugs, each tailored to ease breathing and revitalize the lungs.
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
730
01:20Chronic Obstructive Pulmonary Disease-I: Introduction
3.1K
Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
3.1K