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Research During the Pandemic: Views from Both Sides of the Fence

Bruce Gordon

    Narrative Inquiry in Bioethics
    |August 2, 2021
    PubMed

    Insights

    The COVID-19 pandemic created significant ethical and regulatory challenges for clinical research, impacting clinician scientists globally. Investigators navigated these obstacles, highlighting the need for teamwork and adaptive strategies in human subject research.

    Area of Science:

    • * Clinical Research Ethics
    • * Pandemic Response in Healthcare

    Background:

    • * The COVID-19 pandemic profoundly disrupted global clinical research operations.
    • * Clinician scientists faced unprecedented ethical, regulatory, and oversight challenges.

    Purpose of the Study:

    • * To detail barriers encountered in clinical research during the pandemic.
    • * To explore how investigators coped with these challenges.
    • * To identify common themes, ethical issues, and offer advice for future research.

    Main Methods:

    • * Qualitative analysis of investigator narratives and experiences.
    • * Identification of recurring themes and challenges in clinical trial conduct.

    Main Results:

    • * Common themes included the drive to contribute amidst frustration with obstructions.
    • * Ethical issues were qualitatively and quantitatively different during the pandemic.
    • * Both novel and pre-existing challenges were amplified by the crisis.

    Conclusions:

    • * Clinical research faced unique ethical and logistical hurdles during the pandemic.
    • * Investigator resilience, teamwork, and focus were crucial for navigating challenges.
    • * Lessons learned offer guidance for future pandemic research and human subject protection.

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