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Thrombosis associated with mycoplasma pneumoniae infection (Review)

Jingwei Liu1, Yumei Li1

  • 1Department of Pediatrics Intensive Care Unit, The First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China.

Experimental and Therapeutic Medicine
|August 2, 2021
PubMed

Insights

Mycoplasma pneumoniae infections can cause thrombosis, a blood clotting disorder. While some risk factors are temporary, others are inherited, but most patients recover with prompt treatment.

Area of Science:

  • Infectious Diseases
  • Hematology
  • Pulmonology

Background:

  • Mycoplasma pneumoniae is a common respiratory pathogen.
  • It is increasingly linked to extrapulmonary manifestations, including thrombosis.
  • Thrombosis secondary to Mycoplasma pneumoniae infection is a growing clinical concern.

Purpose of the Study:

  • To review the literature on thrombosis associated with Mycoplasma pneumoniae infection.
  • To understand the pathogenesis, clinical features, treatment, and prognosis of this condition.
  • To enhance the understanding of this crucial clinical issue.

Main Methods:

  • Systematic literature search of PubMed, Medline, and Web of Science.
  • Inclusion of relevant English-language case reports and studies.
  • Synthesis of findings regarding thrombosis in Mycoplasma pneumoniae infections.

Main Results:

  • Thrombosis associated with Mycoplasma pneumoniae can stem from transient or hereditary thrombophilia.
  • Most patients achieve complete recovery with timely treatment.
  • A subset of patients experiences a poor prognosis despite intervention.

Conclusions:

  • Mycoplasma pneumoniae infection presents a significant risk for thrombosis.
  • Understanding the underlying thrombotic factors is crucial for management.
  • Further research is needed to optimize treatment strategies and improve outcomes.
Keywords:
infectionmycoplasma pneumoniaepathogenesisprognosisthrombosis

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