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Updated: Oct 26, 2025

Author Spotlight: Advancing Alzheimer's Research – Exploring Early Detection and Multi-Omics Approaches
Published on: December 15, 2023
A Comparative Analysis of Machine Learning Algorithms to Predict Alzheimer's Disease
Morshedul Bari Antor1, A H M Shafayet Jamil1, Maliha Mamtaz1
1Electrical and Computer Engineering Department, North South University, Dhaka 1229, Bangladesh.
Abstract:
Alzheimer's disease has been one of the major concerns recently. Around 45 million people are suffering from this disease. Alzheimer's is a degenerative brain disease with an unspecified cause and pathogenesis which primarily affects older people. The main cause of Alzheimer's disease is Dementia, which progressively damages the brain cells. People lost their thinking ability, reading ability, and many more from this disease. A machine learning system can reduce this problem by predicting the disease. The main aim is to recognize Dementia among various patients. This paper represents the result and analysis regarding detecting Dementia from various machine learning models. The Open Access Series of Imaging Studies (OASIS) dataset has been used for the development of the system. The dataset is small, but it has some significant values. The dataset has been analyzed and applied in several machine learning models. Support vector machine, logistic regression, decision tree, and random forest have been used for prediction. First, the system has been run without fine-tuning and then with fine-tuning. Comparing the results, it is found that the support vector machine provides the best results among the models. It has the best accuracy in detecting Dementia among numerous patients. The system is simple and can easily help people by detecting Dementia among them.
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