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In Vivo Assessment of Alveolar Macrophage Efferocytosis Following Ozone Exposure
Published on: October 22, 2019
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Ozone eliminates novel coronavirus Sars-CoV-2 in mucosal samples
F Sallustio1, G Cardinale2, S Voccola3
1Department of Interdisciplinary Medicine, University of Bari "Aldo Moro", Bari, Italy.
New Microbes and New Infections
|August 2, 2021
Summary
Ozone gas effectively neutralizes SARS-CoV-2, the virus causing COVID-19, even in high-concentration samples. This study demonstrates ozone
Area of Science:
- Virology
- Infectious Diseases
- Environmental Science
Background:
- Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can persist on surfaces and spread via aerosols.
- Ozone (O3) is known for its biocidal properties, but its specific efficacy against SARS-CoV-2 is not well-established.
Purpose of the Study:
- To investigate the effectiveness of *in situ* generated ozone in inactivating SARS-CoV-2.
- To determine ozone's capacity to neutralize SARS-CoV-2 in nasopharyngeal secretion samples.
Main Methods:
- Exposure of nasopharyngeal secretion samples with high SARS-CoV-2 viral load to ozone generated from oxygen.
- Quantification of viral load before and after ozone treatment to assess inactivation.
Main Results:
- Ozone treatment demonstrated significant efficiency in eliminating SARS-CoV-2.
- The study provides the first evidence of ozone's effectiveness in neutralizing SARS-CoV-2 in realistic sample conditions.
Conclusions:
- Ozone is a potent agent for the inactivation of SARS-CoV-2.
- Ozone treatment presents a promising method for controlling SARS-CoV-2 transmission.
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