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[Indications for using heparin in diffuse suppurative peritonitis in children].

O S Misharev, E P Ivanov, V V Dmitriev

    Vestnik Khirurgii Imeni I. I. Grekova
    |August 1, 1987
    PubMed
    Summary

    Frozen plasma effectively corrects hemostasis in children with diffuse purulent peritonitis. Frozen plasma and heparin are indicated for disseminated intravascular coagulation (DIC) and organ dysfunction, regardless of prior surgery.

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    [Life Threatening Complications in Patients With ST-Elevation Acute Coronary Syndrome-Dependence on Reperfusion Interventions (Data of Federal Register of Patients With Acute Coronary Syndrome)].

    Kardiologiia·2017

    Area of Science:

    • Pediatric Surgery
    • Hematology
    • Critical Care Medicine

    Context:

    • Diffuse purulent peritonitis in children presents a complex clinical challenge.
    • Disturbances in hemostasis are common in pediatric peritonitis.
    • Disseminated intravascular coagulation (DIC) and parenchymal organ insufficiency are critical complications.

    Purpose:

    • To evaluate the efficacy of anti-thrombin (frozen plasma) in correcting disturbed hemostasis in pediatric peritonitis.
    • To establish indications for the use of frozen plasma and heparin in managing complications of peritonitis.

    Summary:

    • In uncomplicated diffuse purulent peritonitis, frozen plasma alone is sufficient for correcting hemostatic disturbances in children.
    • The development of laboratory signs of DIC and clinical evidence of organ dysfunction warrant the use of frozen plasma and heparin.

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  • Treatment decisions regarding frozen plasma and heparin should be made irrespective of previous surgical interventions.

    • Impact:

    • Provides a clear therapeutic guideline for managing hemostatic disorders in pediatric peritonitis.
    • Highlights the importance of early recognition and intervention for DIC and organ dysfunction.
    • Optimizes the use of blood products and anticoagulants in critically ill children.