Arabic Translation and Validation of Olfactory-Specific Quality of Life Assessment Questionnaire

Olfaction plays a critical role in our health, emotions, social life and safety, which is why olfactory dysfunction has a great impact on a person's life. This has been highlighted with the recent coronavirus disease 2019 (COVID-19) pandemic. Despite Arabic being the fifth most commonly spoken language and one of the six official languages of the United Nations, there is no Arabic version for an olfactory-specific quality of life assessment tool.

The Questionnaire of Olfactory Disorders-Negative Statements (QOD-NS) is a validated questionnaire that assesses many aspects of a patient's daily life. We translated this questionnaire to the Arabic language following European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Group Translation Procedure guidelines. A pilot-testing of the Arabic version was done among 20 participants, 10 of whom were confirmed to have normosmia based on scoring at least 11/12 on the Sniffin' Sticks (SS) olfactory testing (Group 1) and another 10 participants who reported anosmia and scored less than 7/12 on the SS test. Patients could agree, partially agree, partially disagree, or disagree with each questionnaire statement.

The pilot study revealed that participants with confirmed anosmia had higher questionnaire scores compared to participants with normosomia (median 22 compared to 1, p value < 0.001). For each statement on the Arabic questionnaire, all questions scored at least 80% of intra-rater reliability, and the overall intra-rater reliability was 90%.

The Arabic translation of QOD-NS is a validated questionnaire that can be used both in academic and clinical practice.