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Preoperative Fasting Time and Its Association with Hypoglycemia during Anesthesia in Pediatric Patients Undergoing
Hussien Endris Assen1, Anissa Mohammed Hassen2, Ananya Abate3
1Department of Anesthesia, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia.
Insights
Prolonged preoperative fasting in children undergoing surgery is common and significantly increases the risk of hypoglycemia during anesthesia. This study highlights the need to re-evaluate fasting guidelines for pediatric patients to ensure their safety and well-being.
Area of Science:
- Anesthesiology
- Pediatric Surgery
- Critical Care Medicine
Background:
- Preoperative fasting is crucial for preventing pulmonary aspiration during anesthesia.
- The impact of extended fasting durations on pediatric glucose levels under anesthesia requires further investigation.
- This study addresses preoperative fasting times and hypoglycemia risk in pediatric patients undergoing elective surgery.
Purpose of the Study:
- To assess preoperative fasting durations in pediatric patients.
- To determine the association between fasting time and hypoglycemia during anesthesia.
- To identify factors contributing to hypoglycemia in this patient group.
Main Methods:
- An institutional-based cross-sectional study involving 258 pediatric patients.
- Systematic sampling, face-to-face interviews, and medical record reviews were employed.
- Binary and multivariable logistic regression analyses identified factors associated with hypoglycemia.
Main Results:
- Mean fasting times from breast milk, solid foods, and clear fluids were 7.75, 13.25, and 12.31 hours, respectively.
- Over a quarter (26.2%) of pediatric patients experienced hypoglycemia post-induction.
- Fasting duration from solid foods, residence, and patient source were significantly linked to hypoglycemia.
Conclusions:
- Pediatric patients undergoing elective procedures often experience prolonged preoperative fasting.
- Extended fasting times are significantly associated with an increased incidence of hypoglycemia during anesthesia.
- Findings suggest a need for revised fasting protocols to mitigate hypoglycemia risk in pediatric surgical patients.
Background:
Preoperative fasting is important to reduce the risk of pulmonary aspiration during anesthesia. The influence of prolonged fasting time on glucose levels during anesthesia in children remains uncertain. Therefore, this study is aimed at assessing preoperative fasting time and its association with hypoglycemia during anesthesia in pediatric patients undergoing elective procedures at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia. The research hypothesis of the study is as follows: there is a prolonged preoperative fasting time, and it influences the glucose levels during anesthesia among pediatric patients undergoing elective procedures at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia.
Methods:
Institutional based cross-sectional study was conducted among 258 pediatric patients who had undergone elective procedures in a tertiary care center. A systematic sampling method was used to select study participants. The data were collected through face-to-face interviews and medical record reviews. Binary logistic regression was used to identify associated factors of hypoglycemia during anesthesia among pediatric patients undergoing elective procedures. All explanatory variables with a p value of ≤0.25 from the bivariable logistic regression model were fitted into the multivariable logistic regression model to control the possible effect of confounders, and finally, the variables which had an independent association with hypoglycemia were identified based on adjusted odds ratio with 95% confidence interval, and a p value less than 0.05 was significant.
Results:
The mean (standard deviation) fasting hours from breast milk, solid foods, and clear fluids were 7.75 (2.89), 13.25 (3.14), and 12.31 (3.22), respectively. The majority (89.9%, 57.9%, and 100%) of participants had fasted from solid, breast milk, and clear fluids for more than 8, 6, and 4 hours, respectively. More than one-fourth (26.2%) of participants were hypoglycemic immediately after induction. Residence, order of nothing per mouth, source of patient, and duration of fasting from solid foods had a significant association with hypoglycemia during anesthesia in children.
Conclusion:
Children undergoing elective procedures were exposed to unnecessarily long fasting times which were associated with hypoglycemia during anesthesia.
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