Conductive Nanodiamond-Based Detection of Neurotransmitters: One Decade, Few Sensors

Nanodiamond (ND) is a class of carbon nanomaterial with covalently connected sp³ carbon atoms in its core and an sp² carbon adorned surface via edge defects or doping. Endogenous chemicals that provoke physiological responses in the human system called neurotransmitters (NTs) have been detected with several sensors with carbon-based nanomaterials. Nanodiamonds (NDs), another class of carbon nanomaterial, have shown the requisite surface area and electrocatalytic activity toward NTs in the past decade. Surprisingly, only a few electrochemical ND based NT sensors are available. This work briefly looked into the performance of the available sensors, NT and ND interactions, and the possible reason for data paucity on the subject matter.