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Updated: Aug 14, 2026

Permanent Ligation of the Left Anterior Descending Coronary Artery in Mice: A Model of Post-myocardial Infarction Remodelling and Heart Failure
Published on: December 2, 2014
[Respiratory disorders following the acute stage of myocardial infarct]
Abstract:
The subject of the study are the respiratory disorders after the acute stage of myocardial infarction. 25 patients, mean age 54 years, were studied. Modern test allowing the detection of the slightest respiratory disorders were used: maximal, mean and end respiratory flow, mean transitory time, calculated from the flow-volume curve. From the nitrogram, accomplished by a fast N2 analyzer, are calculated the closing time and % N2/l index. The interrelation with the gas density was studied by breathing of low density gas mixtures (He--80%, O2--20%). The highest sensitivity showed: % N2/l index, maximal expiratory flow 25%, maximal expiratory flow 50%, mean maximal expiratory flow, maximal end expiratory flow, closing time. The conclusion is that because of the close relations between the cardiovascular system and the lungs the respiratory disorders give indirect information for the degree of myocardial injury.
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