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Updated: Oct 26, 2025

Minimally Invasive Establishment of Murine Orthotopic Bladder Xenografts
Published on: February 11, 2014
Percutaneous Biopsy Tract Seeding in a Patient with Muscle-invasive Bladder Cancer
Andrew Gusev1, Scott Greenberg1, Shubha Dave2
1Department of Urology, University of Massachusetts Medical School, Worcester, MA, USA.
Abstract:
Percutaneous biopsy can be used for tissue diagnosis of bladder tumors when cystoscopy with transurethral resection is not possible. The largest known case series includes 15 patients with no reported complications and good concordance with surgical pathology. However, concern remains regarding exposure of nonurothelial surfaces to tumor cells, as there are rare documented cases of tumor seeding along nephrostomy and biopsy tracts in upper tract urothelial carcinoma (UC). We present the first documented human case of bladder cancer involvement of the omentum and peritoneum along a biopsy tract and review the use of percutaneous access for upper and lower tract UC.

