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Scaffold strategies combined with mesenchymal stem cells in vaginal construction: a review

Nicole Andréa Corbellini Henckes1,2, Dalana Faleiro3,4, Laura Chao Chuang4

  • 1Programa de Pós-Graduação em Ciências da Saúde-Ginecologia e Obstetrícia, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil. nicolecorbellini@hotmail.com.

Cell Regeneration (London, England)
|August 2, 2021
PubMed

Keywords:
Mesenchymal stem cellsScaffoldsTissue engineeringVaginal reconstruction

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Mesenchymal stem cells (MSCs) are adult stem cells that can differentiate into most connective tissue cell types, except for hematopoietic cells, depending upon the source of MSCs. For example, bone-marrow-derived MSCs (BM-MSCs) can differentiate into osteocytes, hepatocytes, and pancreatic and neuronal cells. MSCs can be isolated from various sources such as bone marrow, placenta, adipose tissue, teeth, and Wharton’s jelly, a gelatinous substance in the umbilical cord. The ease of their access...