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Related Concept Videos

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Chronic Obstructive Pulmonary Disease-I: Introduction01:20

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Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
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Chronic Obstructive Pulmonary Disease01:22

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COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
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Updated: Oct 26, 2025

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
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Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

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An update on interstitial lung disease.

D Mudawi1, K Heyes1, R Hastings2

  • 1Interstitial Lung Disease Unit, Respiratory Medicine Department, Wythenshawe Hospital, Manchester, UK.

British Journal of Hospital Medicine (London, England : 2005)
|August 2, 2021
PubMed
Summary
This summary is machine-generated.

Interstitial lung diseases (ILDs) involve lung inflammation and scarring. Diagnosis requires a multidisciplinary approach, while new anti-fibrotic medications offer improved management for these complex conditions.

Keywords:
Connective tissue diseaseDrug-induced interstitial lung diseaseHypersensitivity pneumonitisIdiopathic pulmonary fibrosisInterstitial lung diseaseSarcoidosis

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Author Spotlight: Exploring the Role of Inflammation in the Co-occurrence of Primary Sjogren's Syndrome and Lung Adenocarcinoma
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Author Spotlight: Exploring the Role of Inflammation in the Co-occurrence of Primary Sjogren's Syndrome and Lung Adenocarcinoma
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Area of Science:

  • Pulmonology
  • Internal Medicine
  • Pathology

Background:

  • Interstitial lung diseases (ILDs) are a diverse group of disorders characterized by inflammation and fibrosis of the lung interstitium.
  • Common ILDs include idiopathic pulmonary fibrosis, hypersensitivity pneumonitis, connective tissue disease-associated ILD, sarcoidosis, and drug-induced ILD.

Purpose of the Study:

  • To review the diagnostic and management strategies for common interstitial lung diseases.
  • To highlight the importance of a multidisciplinary approach in ILD diagnosis and care.
  • To discuss recent advancements in ILD management, including anti-fibrotic therapies.

Main Methods:

  • A comprehensive review of diagnostic modalities for ILD.
  • Discussion of key clinical features, laboratory tests, pulmonary function tests, and imaging (high-resolution computed tomography).
  • Consideration of bronchoalveolar lavage and lung biopsy when necessary for multidisciplinary consensus diagnosis.

Main Results:

  • A multidisciplinary approach integrating clinical, radiological, and pathological findings is essential for accurate ILD diagnosis.
  • Disease-modifying anti-fibrotic medications, such as nintedanib and pirfenidone, represent significant advancements in ILD management.
  • Patients with ILD often experience a high symptom burden, necessitating a holistic approach including palliative care.

Conclusions:

  • Accurate diagnosis of interstitial lung diseases relies on a collaborative, multidisciplinary strategy.
  • Emerging anti-fibrotic therapies are transforming the management landscape for ILDs.
  • Comprehensive patient care for ILDs must address symptom burden and palliative needs alongside disease-specific treatments.