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nPEP protocol implementation and evaluation at a local US Crisis Center.

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A program improved access to non-occupational Post-Exposure Prophylaxis (nPEP) for HIV after sexual assault. Most eligible individuals received nPEP and completed it, despite side effects, indicating program effectiveness.

Keywords:
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Area of Science:

  • Public Health
  • Infectious Disease Prevention
  • Sexual Assault Care

Background:

  • Non-occupational Post-Exposure Prophylaxis (nPEP) is recommended for HIV prevention after substantial risk exposures.
  • Barriers to nPEP utilization necessitate improved access and program development.
  • A community sexual assault provider developed a comprehensive nPEP program to address these barriers.

Purpose of the Study:

  • To evaluate the implementation and effectiveness of a newly developed nPEP protocol for sexual assault victims.
  • To identify barriers and facilitators to nPEP uptake and completion in this population.

Main Methods:

  • Retrospective chart review of sexual assault victims over a six-month period.
  • Analysis of nPEP offer, acceptance, and completion rates.
  • Follow-up phone interviews with patients who accepted nPEP.

Main Results:

  • 157 patients presented; 80% within 72 hours.
  • 73% were offered nPEP, 59% accepted.
  • Common reasons for declining nPEP included needing more time.
  • 77% of contacted patients completed nPEP; side effects were a common reason for noncompletion.
  • 84% of eligible patients were offered nPEP, aligning with CDC guidelines.

Conclusions:

  • The developed nPEP program demonstrated good adherence to guidelines and effective implementation.
  • Despite challenges like side effects, most patients completed nPEP, indicating its value.
  • Findings highlight opportunities to further optimize the nPEP process for sexual assault survivors.