Related Experiment Video
Updated: Oct 26, 2025

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats
Published on: May 22, 2019
[Ischemic stroke in coronavirus disease 2019]
Paulina Laura Sander1, Ulrich Cleff1, Simon Larrossa-Lombardi2
1Klinik für Neurologie, Knappschaftskrankenhaus Dortmund - Klinikum Westfalen, Am Knappschaftskrankenhaus 1, 44309, Dortmund, Deutschland.
Insights
Coronavirus disease 2019 (COVID-19) can cause severe stroke in younger patients due to blood clot formation. Early intervention with thrombolysis and thrombectomy can improve outcomes in these critical cases.
Area of Science:
- Neurology
- Infectious Diseases
- Cardiology
Background:
- Coronavirus disease 2019 (COVID-19) is associated with a hypercoagulable state.
- Cerebral artery occlusion is a rare but serious complication of COVID-19.
- Stroke can occur in patients of all ages with COVID-19.
Abstract:
This article reports two cases of patients with coronavirus disease 2019 (COVID-19) in which occlusion of large cerebral arteries occurred. These occurred in a female patient in the early stage of COVID-19 and in the second case in the late stage. One female patient could be successfully treated with i.v. thrombolysis and mechanical thrombectomy. Coagulopathy in the course of COVID-19 can result in severe stroke with poor outcome even in younger patients. With respect to the etiology of arterial occlusions (COVID-19-induced hypercoagulopathy, cardiomyopathy, vasculitis) there is a necessity for further research.
Related Concept Videos
Ischemic Heart Disease: Overview
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
Regulation of Stroke Volume
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
Coronary Artery Disease I: Introduction
Acute Coronary Syndrome I: Introduction
Coronary Artery Disease III: Clinical Manifestations

