[Course of illness in malignant primary tumors with skeletal metastases]

About 70,000 malignant primary tumors with skeleton metastases are regarded with respect to tumor age, survival time with metastases respectively with primary tumor and life expectancy. Some cases with mamma carcinoma showed the vertebral type of bone metastasizing whereas the other primary tumors showed the typical type of spreading metastases over the lung. Patients with skeleton metastases are younger than the others. They have a longer survival time than the other patients without bone metastases but they die earlier. In those cases in which the primary tumor was diagnosed because of bone metastases without any earlier tumor treatment the survival time with metastases was longer than in other patients. Metastases with low grade histological differentiation were more often to be seen in patients who got their primary tumor in younger age. These metastases arose in a relatively late stage of the disease.