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The psychosis human connectome project: An overview
Caroline Demro1, Bryon A Mueller2, Jerillyn S Kent2
1Department of Psychiatry and Behavioral Sciences, University of Minnesota, Minneapolis, MN, United States; Department of Psychology, University of Minnesota, Minneapolis, MN, United State.
Neuroimage
|August 2, 2021
Summary
The psychosis Human Connectome Project (P-HCP) collected multimodal data, including MRI, to study brain disorders. This publicly available dataset aids researchers investigating psychotic psychopathology and its genetic links.
Area of Science:
- Neuroscience
- Psychiatry
- Genetics
Background:
- Human Connectome Project expanded to investigate brain disorders.
- Psychotic disorders are a focus of new research initiatives.
- Understanding neural mechanisms in psychosis is crucial.
Purpose of the Study:
- Describe the psychosis Human Connectome Project (P-HCP) investigation.
- Outline the data acquisition process for the P-HCP dataset.
- Facilitate future research using publicly available P-HCP data.
Main Methods:
- Collected multimodal data: clinical, cognitive, motor, genetic, and MRI.
- Utilized 3 Tesla MRI for neuroimaging acquisition.
- Developed experimental tasks to probe neural functions related to psychosis.
Main Results:
- The P-HCP dataset is comprehensive and multimodal.
- Data acquisition protocols are detailed for researcher use.
- The dataset includes participants characterized for psychopathology.
Conclusions:
- The P-HCP provides a valuable resource for studying psychotic disorders.
- Publicly accessible data will advance research on psychosis.
- This project supports investigations into the genetic liability of psychotic psychopathology.
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