Low monoenergetic DECT detection of pyelonephritis extent

To determine whether contrast enhanced DECT low monoenergetic can improve diagnostic conspicuity of inflamed kidney foci in acute pyelonephritis compared to conventional images.

A retrospective study of 45 patients with clinical signs of acute pyelonephritis undergoing contrast-enhanced exams on a single source-DECT was conducted. Representative conventional and monoenergetic images were randomized and presented to four abdominal radiologists to determine their preference for inflamed kidney foci detection, and to determine the number of foci identified. Clinical impact of monoenergetic images was assessed using multivariant analysis. Contrast and signal to noise ratios were compared between the images using paired t-tests.

A greater number of foci were detected on the low energetic images for each patient (6.4 ± 5.3 vs. 4.2 ± 3.8, p < 0.02). Additionally, a consistent linear increase in the number of detected foci on the monoenergetic compared to the conventional images was seen (y = 0.10X + 0.36 R² = 0.76). Most notably, in 16% of kidneys a clearly definable focus was detected only on monoenergetic images. SNR and CNR were increased by 2 and 1.5 fold for monoenergetic compared to conventional images (p < 0.001). Monoenergetic images were preferred by all readers for detecting inflamed foci (162/180 reads, P < 0.05), with 79% interreader reliability.

Low monoenergetic images enable increased detection of inflamed kidney parenchyma, and permit identification of pathologic foci some of which were not seen on the conventional images. Along with the strong preference of radiologists, these images should be considered beneficial for evaluating acute pyelonephritis.