Related Experiment Video
Updated: Oct 26, 2025

Improving Student Outcomes with an Adaptable Molecular Cloning Course-Based Undergraduate Research Experience
Published on: November 15, 2024
Effectiveness and perceptions of MBBS students about process-oriented guided inquiry learning in biochemistry
Smita S Sonoli1, Shrimanjunath Sankanagoudar2
1Department of Biochemistry, K.L.E. Academy of Higher Education (KAHER) Jawaharlal Nehru Medical College, Belagavi, Karnataka, India.
Student feedback revealed dissatisfaction with traditional lectures. Implementing process-oriented guided inquiry learning (POGIL) improved knowledge retention and problem-solving skills, especially for low achievers in biochemistry.
Area of Science:
- Medical Education
- Biochemistry Pedagogy
Background:
- Students expressed dissatisfaction with traditional lecture-based teaching methods.
- Concerns were raised regarding knowledge retention and problem-solving abilities.
- A need for improved teaching methodologies was identified.
Purpose of the Study:
- To analyze the effectiveness of Process-Oriented Guided Inquiry Learning (POGIL) sessions.
- To evaluate student perceptions of POGIL as a supplementary teaching strategy.
- To assess POGIL's impact on knowledge retention and problem-solving in biochemistry.
Main Methods:
- A study involving 42 first-year MBBS students (42 participants, 7 groups) was conducted.
- One-hour POGIL sessions were implemented weekly, following lectures and provided reading materials.
- Effectiveness was assessed using pre-, post-, and retention multiple-choice questions (MCQs), and perceptions were gathered via questionnaires.
Main Results:
- Statistically significant improvements in MCQ scores were observed in post-tests and retention tests compared to pre-tests for all students and low achievers (p<0.05).
- Approximately 60% of students reported that POGIL activities and teamwork enhanced their conceptual understanding.
- Reflection analysis identified key learning areas and prompted students to develop memory aids for complex topics.
Conclusions:
- Process-Oriented Guided Inquiry Learning (POGIL) shows promise as a reinforcement strategy for biochemistry lectures.
- POGIL is a potentially valuable tool for addressing learning challenges faced by low-achieving students.
- The methodology effectively improved student engagement and concept mastery.
Related Concept Videos
Bioavailability Enhancement: Determination and Conceptual Approaches in Overcoming Bioavailability Problems
Introduction to Enzyme Kinetics
The experimenter can then plot the initial reaction rate or velocity (Vo) of a given trial against the substrate concentration ([S]) to obtain a graph of the reaction properties. For many enzymatic reactions involving a...
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Outcomes of Glycolysis
Cellular respiration can occur aerobically (with oxygen) or anaerobically (without oxygen). In the presence of oxygen, cellular respiration starts with glycolysis and continues with pyruvate...
Factors Affecting Dissolution: Drug Permeability, Stability and Stereochemistry

