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Updated: Oct 26, 2025

The Resident-intruder Paradigm: A Standardized Test for Aggression, Violence and Social Stress
Published on: July 4, 2013
Risk factors for inducing violence in patients with delirium
Masako Tachibana1,2, Toshiya Inada2,3, Masaru Ichida1
1Department of Psychiatry, Nagoya Ekisaikai Hospital, Nagoya-shi, Aichi, Japan.
Current smokers, older age, male gender, and ICU stays are linked to violence in delirium patients. Early assessment and management can prevent aggressive incidents and reduce restraints.
Area of Science:
- Geriatric Medicine
- Psychiatry
- Clinical Medicine
Background:
- Delirium can cause sudden, unpredictable violence.
- Identifying factors associated with violence is crucial for prevention.
- Minimizing restraint and sedation is a key goal in managing delirium.
Purpose of the Study:
- To identify demographic, clinical, and pharmacological factors associated with violence in delirium patients.
- To compare characteristics of violent versus non-violent delirium cases.
- To inform strategies for preventing violence in delirium.
Main Methods:
- Retrospective analysis of 601 delirium cases over 5 years.
- Comparison of violent (n=189) and non-violent (n=412) patient groups.
- Logistic regression analysis to determine significant factors.
Main Results:
- Current smoker status (p < .0005) was strongly associated with violence.
- Older age (p < .0005) and male gender (p = .004) were significant risk factors.
- Intensive care unit (ICU) admission (p = .043) also correlated with increased violence.
Conclusions:
- Screening tools and proactive management can improve outcomes for patients and staff.
- Further research is needed on nicotine replacement therapy for violence prevention during nicotine withdrawal.
- Evaluating the safety of interventions for elderly inpatients with delirium is important.
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