Related Experiment Video
Updated: Oct 25, 2025
12:30
Monitoring ER/SR Calcium Release with the Targeted Ca2+ Sensor CatchER+
Published on: May 19, 2017
15.1K
Strontium increasing calcium accessibility from calcium citrate
Xiao-Chen Liu1, Leif H Skibsted1
1Department of Food Science, University of Copenhagen, Rolighedsvej 26, DK-1958 Frederiksberg C, Denmark.
Food Chemistry
|August 3, 2021
Summary
Strontium chloride increases calcium ion activity in metastable calcium citrate tetrahydrate suspensions. This occurs due to the formation of less soluble strontium citrate pentahydrate, impacting biomineralization processes.
Area of Science:
- Inorganic Chemistry
- Solution Chemistry
- Biomineralization
Background:
- Metastable calcium citrate tetrahydrate is a precursor in biomineralization.
- Understanding ion interactions is crucial for controlling mineral formation.
Purpose of the Study:
- To investigate the effect of strontium chloride on calcium ion activity in calcium citrate tetrahydrate suspensions.
- To elucidate the thermodynamic differences in calcium and strontium citrate complexation.
Main Methods:
- Electrochemical measurements to determine calcium ion activity.
- Differential Scanning Calorimetry (DSC) to assess phase transitions.
- Electric conductivity measurements to study binding thermodynamics.
Main Results:
- Strontium chloride addition increased calcium ion activity without phase transition.
- Strontium citrate pentahydrate exhibited lower solubility than calcium citrate tetrahydrate.
- Thermodynamic analysis revealed distinct binding enthalpies for strontium and calcium citrate.
Conclusions:
- Solubility differences and binding thermodynamics explain the observed calcium ion activity changes.
- These findings provide insights into the role of ion interactions in biomineralization.
Related Concept Videos
01:21Skeleton and Calcium Homeostasis
5.1K
Calcium is not only the most abundant mineral in bone but also the most abundant mineral in the human body. Calcium ions are needed for bone mineralization, tooth health, heart rate regulation and strength of contraction, blood coagulation, the contraction of smooth and skeletal muscle cells, and the regulation of nerve impulse conduction. The average calcium level in the blood is about 10 mg/dL. When the body cannot maintain this level, a person will experience hypo or hypercalcemia.
5.1K
01:19Ionic Strength: Effects on Chemical Equilibria
2.0K
The addition of an inert ionic compound increases the solubility of a sparingly soluble salt. For example, adding potassium nitrate to a saturated solution of calcium sulfate significantly enhances the solubility of calcium sulfate. Le Châtelier's principle cannot predict this shift in the equilibrium. Instead, this could be explained in terms of changes in the effective concentration of the ions in solution in the presence of added inert salt.
In this solution, the primary...
In this solution, the primary...
2.0K
01:27Feedback Regulation of Calcium Concentration
3.5K
Calcium is an essential signaling molecule required for various cellular functions. Calcium pumps and ion channels on cell and organellar membranes, such as those on the endoplasmic reticulum (ER), regulate calcium concentrations inside the cell. They remain closed, keeping the cytosolic calcium levels low at a resting state.
Various transmembrane receptors, such as G protein-coupled receptors (GPCRs), elicit a response to extracellular signals by increasing cytosolic calcium. Activated GPCRs...
Various transmembrane receptors, such as G protein-coupled receptors (GPCRs), elicit a response to extracellular signals by increasing cytosolic calcium. Activated GPCRs...
3.5K
01:17Hormones and Bone Tissue
3.2K
The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
3.2K
01:31Essential Minerals for Bone Health
4.9K
The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
4.9K
04:01Factors Affecting Solubility
34.9K
Compared with pure water, the solubility of an ionic compound is less in aqueous solutions containing a common ion (one also produced by dissolution of the ionic compound). This is an example of a phenomenon known as the common ion effect, which is a consequence of the law of mass action that may be explained using Le Chȃtelier’s principle. Consider the dissolution of silver iodide:
34.9K