Related Experiment Video
Updated: Jun 26, 2026

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia
Published on: December 19, 2020
Kikuchi-Fujimoto disease presenting in a patient with SARS-CoV-2: a case report
Samuel D Racette1, Borislav A Alexiev2, Michael P Angarone3
1Department of Otolaryngology-Head and Neck Surgery, Feinberg School of Medicine, Northwestern University, 676 N. St. Clair Street, Suite 1325, Chicago, IL, 60611, USA. samuel.racette@northwestern.edu.
Background:
We present a yet to be described association of SARS-CoV-2 infection with Kikuchi-Fujimoto disease.
Case Presentation:
A 32-year-old physician with history of SARS-CoV-2 infection presented to the emergency department with 2 weeks of fever, chills, and right sided cervical lymphadenopathy. He was treated empirically for presumed folliculitis with worsening of symptoms leading to repeat presentation to the emergency department. Extensive workup was unrevealing of an infectious cause and needle biopsy of the lesion was unrevealing. An excisional lymph node biopsy revealed follicular hyperplasia with necrotic foci showing abundance of histiocytes at the edge of necrosis with CD8 predominance of T-cells. Final diagnosis was deemed to be Kikuchi-Fujimoto disease. Antibiotic therapy was discontinued, and the patient's symptoms resolved with steroid therapy and expectant management.
Conclusions:
This is the first report of a patient developing Kikuchi-Fujimoto disease following SARS-CoV-2 infection. Clinicians should be aware of Kikuchi-Fujimoto disease as a possibility when approaching patients with hyper-inflammatory states who present with cervical lymphadenopathy.
More Related Videos
Related Concept Videos
Endocarditis II: Clinical Features of Infective Endocarditis
Infectious Diseases and Their Occurrence
Investigation of Disease Outbreaks
Cytomegalovirus Disease
Influenza
Coronavirus

