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Recurrent solitary bone plasmacytoma: A case report.
Rajendra Sakhrekar1, Ketan Khurjekar1, Shailesh Hadgaonkar1
1Department of Spine Surgery, Sancheti Institute of Orthopedics and Rehabilitation, Pune, Maharashtra, India.
Surgical Neurology International
|August 4, 2021
Summary
Plasmacytoma can progress to multiple myeloma (MM), a condition that may cause neurological symptoms. Surgical intervention is often necessary for spinal lesions that are resistant to conventional treatments.
Area of Science:
- Oncology
- Neurosurgery
- Hematology
Background:
- Plasmacytoma is a bone-originating hematological malignancy.
- It can affect a single skeletal site but progresses to multiple myeloma (MM) in 50% of cases.
- MM involves widespread skeletal lesions.
Observation:
- A 73-year-old patient with a history of plasmacytoma presented with progressive paraparesis.
- Neurological examination revealed lower extremity weakness, hyperreflexia, and Babinski signs.
- The patient underwent spinal decompression, corpectomy, reconstruction, and fusion.
Findings:
- Patients with plasmacytoma have a 50% risk of developing neurological symptoms due to evolving multiple myeloma.
- Spinal lesions from MM can be refractory to radiation and chemotherapy.
Implications:
- Surgery is frequently indicated for managing neurological deficits caused by spinal MM.
- Early surgical intervention may be crucial for patients with plasmacytoma progression to MM.
