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Updated: Oct 25, 2025

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High-Frequency Percussive Ventilation in Cystic Fibrosis Patients With Acute Respiratory Failure: A Case Series
Badr Jandali1, Joel D Mermis1, Michael S Crosser1
1Pulmonary and Critical Care Medicine, The University of Kansas Health System, Kansas City, USA.
Abstract:
Acute respiratory failure in cystic fibrosis carries a high risk of mortality. The optimal mode of mechanical ventilation (MV) in this population is not well established. In this case series, we identified patients with cystic fibrosis who were ventilated with high-frequency percussive ventilation (HFPV) at our institution and describe their characteristics and outcomes. The use of high-frequency percussive ventilation has been sparsely described in the literature. This case series could serve as hypothesis-generating for future research.
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