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Updated: Oct 25, 2025

MicroRNA Amplification and Recognition through Locked-nucleic-acid In situ Hybridization as A Novel Detection and Quantification Method
Published on: October 7, 2025
Biomineralized zeolitic imidazolate framework-8 nanoparticles enable polymerase/endonuclease synergetic amplification
Ke Zhang1, Xiayun Le, Qiaoqin Yu
1State Key Laboratory of Chemo/Bio-Sensing and Chemometrics, College of Chemistry and Chemical Engineering, Changsha, China.
Abstract:
In this work, we have implemented a polymerase and endonuclease synergetic amplification reaction in living cells for intracellular miRNA imaging by using biomineralized ZIF-8 NPs.
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