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Published on: February 4, 2014
[Pharmacobezoar in a woman with a clomipramine intoxication]
A K Sandhu1,2, A M van Schip3, L Driessen4
1Spaarne Gasthuis locatie Hoofddorp en Haarlem, afd. Interne Geneeskunde.
Background:
Medicines with controlled release can cause a rare phenomenon, known as pharmacobezoar, following overdose of these medications.
Case Description:
A case of a 56-year-old women with severe clomipramine intoxication is described. X-ray of the abdomen showed a cluster of tablets in the caecum. Lab results showed severe plasma concentration of clomipramine. Patient was treated with active coal and remained stable.
Conclusion:
It is important to be aware of the presence of pharmacobezoar in intoxication with controlled release medicines. The formation of pharmacobezoar can lead to unpredictable duration of intoxication.
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