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Physiology Lab Demonstration: Glomerular Filtration Rate in a Rat
Published on: July 26, 2015
[Can furosemide mask the use of performance-enhancing drugs?]
D J Brinkman1,2, J Tichelaar1, M A Van Agtmael1
1Amsterdam UMC, locatie VUmc, afd. Interne Geneeskunde, sectie Farmacotherapie, Amsterdam (tevens: Research and Expertise Center In PharmacotherapyEducation (RECIPE), Amsterdam).
Abstract:
Furosemide is included in the World Anti-Doping Agency's (WADA) list of prohibited substances because it can be used by athletes to mask the presence of performance-enhancing drugs in urine and/or excrete water for rapid weight loss. But how effective is furosemide in masking prohibited substances in urine? Based on the pharmacology and the available literature, we conclude that the masking effect of furosemide is limited. Furosemide is a doping agent that is mainly relevant for sports with weight categories.
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