Related Experiment Video
Updated: Oct 25, 2025
Anionic Polymerization of an Amphiphilic Copolymer for Preparation of Block Copolymer Micelles Stabilized by π-π Stacking Interactions
Published on: October 10, 2016
Stimuli-Responsive Block Copolymer Micelles Based on Mussel-Inspired Metal-Coordinated Supramolecular Networks
Ritabrata Ganguly1, Pabitra Saha2,3, Sovan Lal Banerjee1
1Rubber Technology Centre, Indian Institute of Technology Kharagpur, 721302, India.
Abstract:
Amphiphilic diblock copolymers containing dopamine and zwitterions are synthesized via the RAFT polymerization method, which undergo temperature-mediated micellization in aqueous media. The presence of catechol moiety in dopamine is exploited to form pH-responsive cross-links with ferric ions (Fe3+ ) at different pH value. Herein, a comprehensive study of the effect of pH as well as temperature on the size and solution behavior of these cross-linked micelles is presented. These micelles cross-linked via metal-catechol coordination bonds can have several important biomedical applications such as degradable scaffolds for payload delivery.
