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C1-Inhibitor: Structure, Functional Diversity and Therapeutic Development

Elena Karnaukhova1

  • 1Laboratory of Biochemistry and Vascular Biology, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland 20993,United States.

Current Medicinal Chemistry
|August 5, 2021
PubMed
Summary

Human C1-Inhibitor (C1INH) is a key anti-inflammatory protein. Research explores its role beyond Hereditary Angioedema (HAE), investigating C1INH therapies for sepsis, shock, and COVID-19 complications.

Keywords:
C1-inhibitorC1-inhibitor productscomplementcontact systemhereditary angioedematherapeutic development.

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