Correlation Analysis of Breast and Thyroid Nodules: A Cross-Sectional Study

Area of Science:

• Endocrinology
• Oncology
• Radiology

Background:

• Breast mass (BM) and thyroid nodule (TN) are common findings in women.
• Understanding the relationship between BM and TN is crucial for comprehensive health screening.

Purpose of the Study:

• To investigate the association between breast mass and thyroid nodule prevalence.
• To identify factors influencing the occurrence of both breast masses and thyroid nodules.

Main Methods:

• A retrospective study of 12,538 female subjects undergoing simultaneous breast and thyroid ultrasound examinations.
• Univariate, multivariate logistic regression, and propensity score matching analyses were employed.

Main Results:

• Prevalence of BM was 39.7%, and TN was 50.4%; 20.4% had both.
• Thyroid nodules were associated with an increased likelihood of breast masses (OR=1.185).
• Breast masses were associated with an increased likelihood of thyroid nodules (OR=1.180).
• Age, thyroid hormones (free T3, free T4), HDL, height, BMI, blood pressure, and albumin were identified as independent factors for BM and TN.

Conclusions:

• A bidirectional pathogenic relationship exists between breast masses and thyroid nodules.
• Women with breast masses have a higher risk of developing thyroid nodules, and vice versa.
• Thyroid hormone levels play a role in the development of both breast masses and thyroid nodules.