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The Roles of Tetramethylpyrazine During Neurodegenerative Disease
Zeyu Meng1, Huize Chen2, Shengxi Meng3
1The Second Clinical Medical College, Heilongjiang University of Chinese Medicine, Heilongjiang, 150040, China.
Abstract:
With the aging of the world population, neurodegenerative diseases are considered crippling diseases, which seriously affect the quality of life and are an increasing burden on society and the economy. As a major alkaloid in Ligusticum chuanxiong Hort, tetramethylpyrazine (TMP) plays an increasingly significant role during neurodegenerative diseases, including roles as an anti-inflammatory, antioxidative, antiplatelet citatory poisoning, and anti-inflammation. This review focuses on the latest advances in the roles and mechanisms of action of TMP in neurodegenerative diseases to stimulate new concepts and methods for the prevention and treatment of neurodegenerative diseases.
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