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A common language for Gulf War Illness (GWI) research studies: GWI common data elements.
Devra E Cohen1, Kimberly A Sullivan2, Rebecca B McNeil3
1Miami VA Healthcare System, Miami, FL, United States; Institute for Neuro Immune Medicine, Dr. Kiran C. Patel College of Osteopathic Medicine, Nova Southeastern University, Fort Lauderdale, FL, United States.
Life Sciences
|August 5, 2021
Summary
Common Data Elements (CDEs) were developed for Gulf War Illness (GWI) research to standardize data collection and analysis. These CDEs will improve data quality and facilitate sharing across the GWI research community.
Area of Science:
- Medical Research
- Veterans Health
- Data Standardization
Background:
- Gulf War Illness (GWI) research requires standardized data collection for effective analysis and collaboration.
- Previous initiatives for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) provided a foundation for GWI CDE development.
Purpose of the Study:
- To develop Common Data Elements (CDEs) for Gulf War Illness (GWI) research.
- To standardize data collection, analysis, and sharing within the GWI research community.
Main Methods:
- A working group of GWI advocates, Veterans, clinicians, and researchers convened to establish consensus.
- Reviewed and adapted instruments and guidelines from the NINDS ME/CFS CDE initiative.
- Sub-groups focused on symptoms and systems assessment, including deployment exposures.
Main Results:
- GWI CDE recommendations encompass 12 domains, including instruments, case report forms, and guidelines.
- Recommendations are categorized as core, supplemental-highly recommended, supplemental, and exploratory.
- The CDEs will be continually updated as GWI research evolves.
Conclusions:
- The developed GWI CDEs represent a consensus among research community stakeholders.
- Implementation of GWI CDEs will enhance data quality and facilitate research collaboration.
- Standardized data collection is crucial for advancing understanding and treatment of GWI.
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