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Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2
Published on: November 5, 2021
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Animals, vaccines, and COVID-19
1Oregon State University, 322 Milam Hall, Corvallis, OR 97331, USA.
Endeavour
|August 5, 2021
Summary
Animals are crucial to the COVID-19 pandemic, from its origin to vaccine development. Understanding human-animal interactions is key for preventing future zoonotic diseases and improving global health strategies.
Area of Science:
- Veterinary Medicine
- Epidemiology
- One Health
Background:
- The COVID-19 pandemic highlights the significant role of animals, particularly mammals, in disease emergence and spread.
- Zoonotic diseases, like COVID-19, demonstrate the interconnectedness of human and animal health.
- Animals have historically been vital in medical advancements, including vaccine development.
Purpose of the Study:
- To emphasize the critical role of animals in the COVID-19 pandemic.
- To underscore the bidirectional transmission of SARS-CoV-2 between humans and animals.
- To advocate for an interdisciplinary medical approach integrating human and animal health.
Main Methods:
- Review of existing literature on animal involvement in COVID-19.
- Analysis of zoonotic disease transmission patterns.
- Historical perspective on animal use in vaccine research.
Main Results:
- COVID-19 originated in animals, with ongoing transmission between animal and human populations.
- Animals have been instrumental in the research and development of COVID-19 vaccines.
- The pandemic underscores the need to study human-animal interfaces for disease control.
Conclusions:
- An interdisciplinary, One Health approach is essential for managing zoonotic diseases.
- Continued research into animal-human disease dynamics is critical for pandemic preparedness.
- Integrating veterinary and human medicine is vital for global health security.
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